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Cialis (Tadalafil) 2 tabs (20 mg), Eli Lilly

Model 2 tabs 20 mg
Manufacturer Eli Lilly
Price:   $33.00
Reviews

Cialis (Tadalafil) 2 tabs (20 mg), Eli Lilly

Manufacturer: Eli Lilly
Pharmaceutical name: Tadalafil
Pack: 2 tabs (20 mg)


WHAT IS CIALIS?

Cialis (tadalafil) is a drug used to treat erectile dysfunction and an enlarged prostate. It is part of the same “family” of drugs as Viagra (sildenafil), but there are important differences. Both drugs are called PDE-5 inhibitors and you can read more about how they work here.

Cialis (tadalafil) can also be used to treat premature ejaculation (P.E.), especially in people who have both E.D. and P.E.

Tadalafil (INN) is a PDE5 inhibitor marketed in pill form for treating erectile dysfunction (ED) under the names Cialis.



HOW IT WORKS?

Cialis (tadalafil) is nicknamed “The Weekender Pill” because it lasts up to 36 hours. Some people prefer Cialis (tadalafil) because it lasts longer than Viagra (sildenafil) which typically last up to 8 hours.

Here is a quick breakdown:

Cialis (Tadalafil) Viagra (Sildenafil) Levitra (Vardenafil)
  • Works in as quickly as 30 Minutes
  • Median time to take effect 2 hours
  • Lasts up to 36 hours
  • Works in as quickly as 30 Minutes
  • Median time to take effect 1 hour
  • Lasts up to 8 hours
  • Works in as quickly as 30 Minutes
  • Median time to take effect 1 hour
  • Lasts up to 8 hours

Cialis (Tadalafil) relaxes muscles and increases blood flow to particular areas of the body. Cialis is used to treat erectile dysfunction (impotence) in men. Adcirca, another brand of tadalafil, is used to treat pulmonary arterial hypertension and improve exercise capacity in men and women.

Do not take Cialis if you are allergic to Tadalafil, or if you are also using a nitrate drug for chest pain or heart problems, including nitroglycerin, isosorbide dinitrate, and isosorbide mononitrate, or recreational drugs such as amyl nitrate or nitrite. Taking Cialis with a nitrate medicine can cause a sudden and serious decrease in blood pressure.

If you become dizzy or nauseated during sexual activity, or if you have pain, numbness, or tingling in your chest, arms, neck, or jaw, stop and call your doctor right away. You could be suffering from a serious side effect of this medicine.

Do not take Cialis more than once a day. Allow 24 hours to pass between doses. Contact your doctor or seek emergency medical attention if your erection is painful or lasts longer than 4 hours. A prolonged erection (priapism) can damage the penis.

Cialis can decrease blood flow to the optic nerve of the eye, causing sudden vision loss. This has occurred in a small number of people taking Cialis, most of whom also had heart disease, diabetes, high blood pressure, high cholesterol, or certain pre-existing eye problems, and in those who smoke or are over 50 years old. It is not clear whether Cialis is the actual cause of vision loss.

If you have any of these other conditions, you may need a Cialis dose adjustment or special tests: heart disease or heart rhythm problems; a recent heart attack (within the past 90 days); a recent history (in the past 6 months) of a stroke, or congestive heart failure; angina (chest pain), high or low blood pressure; liver disease; kidney disease (or if you are on dialysis); a blood cell disorder such as sickle cell anemia, multiple myeloma, or leukemia; a bleeding disorder such as hemophilia; a stomach ulcer; retinitis pigmentosa (an inherited condition of the eye); a physical deformity of the penis (such as Peyronie's disease); or if you have been told you should not have sexual intercourse for health reasons.

FDA pregnancy category B. Cialis is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether tadalafil passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Side effects: headaches, hearing loss, blurred or color tinged vision and/or sensitivity to light, acid indigestion, flushing, nasal congestion.






POPULAR QUESTIONS

Can I use Cialis with alcohol?

Physicians should inform patients that substantial consumption of alcohol (e.g., 5 units or greater) in combination with CIALIS can increase the potential for side effects.


Can I take Cialis more than once per day?

No. Do not exceed one dose in a 24 hour period.


Is Cialis affected by food?

You can eat normally. Except, it is worth noting grapefruit juice can possibly affect the absorption of Cialis (Tadalafil).


Can I get a Cialis prescription online?

Yes, you can get a prescription through a Roman online visit for Erectile Dysfunction or an online visit for Premature Ejaculation, if determined appropriate by a U.S. licensed physician.




THE NITTY GRITTY

Note: These highlights do not include all the information needed to use CIALIS safely and effectively.


DOSAGE FORMS AND STRENGTHS:

Cialis is made in 2.5 mg, 5 mg, 10 mg, and 20 mg.


DOSES AND ADMINISTRATION:

When Taken As Needed:

The starting dose is usually 10 mg as needed prior to sexual activity but it depends on the individual. It has been shown to improve erectile function, compared to placebo, up to 36 hours post dose.

Based on effectiveness and tolerability, your physician may recommend an increase to 20 mg or a decrease to 5 mg.

Cialis should not to be taken more than once per day.

When Taken Daily:

The starting dose is 2.5 mg, taken at approximately the same time every day, without regard to timing of sexual activity. Based on effectiveness and tolerability, your physician may recommend an increase to 5 mg.


ABSORPTION

Cialis has been shown to take effect in as little as 30 minutes. The median time is 2 hours.

After single oral-dose administration, the maximum observed plasma concentration (Cmax) of tadalafil is achieved between 30 minutes and 6 hours (median time of 2 hours).

Absolute bioavailability of tadalafil following oral dosing has not been determined. The rate and extent of absorption of tadalafil are not influenced by food; thus CIALIS may be taken with or without food.

This differs based on patient population (e.g., Geriatrics). For more information, please read the FDA Prescribing Information.


CONTRAINDICATIONS:

Use of cialis in any patient using any form of organic nitrate is contraindicated. Cialis was show to potentiate the hypotensive effect of nitrates. Simply put, both nitrates and Cialis can lower your blood pressure so the combination of the two can be extremely dangerous.


ADVERSE REACTIONS:

Most Common (≥2%):

Include: headache, dyspepsia, back pain, myalgia, nasal congestion, flushing, and pain in limb

Less Common:

For a complete list of less common side effects, please read the FDA information.

To report SUSPECTED ADVERSE REACTIONS, contact Eli Lilly and Company at 1-800-LillyRx (1-800-545-5979) or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch


WARNINGS AND PRECAUTIONS

  1. Patients should not use Cialis if sex is inadvisable, especially due to cardiovascular status.
  2. Use of CIALIS with alpha blockers, antihypertensives or substantial amounts of alcohol (≥5 units) may lead to hypotension.
  3. CIALIS is not recommended in combination with alpha blockers for the treatment of BPH because efficacy of the combination has not been adequately studied and because of the risk of blood pressure lowering. Caution is advised when CIALIS is used as a treatment for ED in men taking alpha blockers.
  4. If taking potent inhibitors of CYP3A4, dose should be adjusted: CIALIS for use as needed: ≤10 mg every 72 hours. For once daily use: dose not to exceed 2.5 mg.
  5. Patients should seek emergency treatment if an erection lasts >4 hours.
  6. Use CIALIS with caution in patients predisposed to priapism.
  7. Patients should stop CIALIS and seek medical care if a sudden loss of vision occurs in one or both eyes, which could be a sign of Non Arteritic Ischemic Optic Neuropathy (NAION). Physicians should discuss increased risk of NAION in patients with history of NAION.
  8. Patients should stop CIALIS and seek prompt medical attention in the event of sudden decrease or loss of hearing.
  9. Prior to initiating treatment with CIALIS for BPH, consideration should be given to other urological conditions that may cause similar symptoms.

DRUG INTERACTIONS

  • CIALIS can potentiate the hypotensive effects of nitrates, alpha blockers, antihypertensives or alcohol.
  • CYP3A4 inhibitors (e.g. ketoconazole, ritonavir) increase CIALIS exposure. For concomitant use with potent CYP3A4 inhibitors, dose adjustment may be needed.
  • CYP3A4 inducers (e.g. rifampin) decrease CIALIS exposure.

USE IN SPECIFIC POPULATIONS

Hepatic Impairment:

  • Mild or Moderate: Dosage adjustment may be needed.
  • Severe: Use is not recommended.

Renal Impairment:

  • Patients with creatinine clearance 30 to 50 mL/min: Dosage adjustment may be needed.
  • Patients with creatinine clearance less than 30 mL/min or on hemodialysis: For use as needed: Dose should not exceed 5 mg every 72 hours. Once daily use is not recommended.